Sending out an SOS

Timeline: Sending Out an SOS

Sending Out an SOS: Mitochondria as a Signaling Hub

Normal cellular physiology is critically dependent on numerous mitochondrial activities including energy conversion, cofactor and precursor metabolite synthesis, and regulation of ion and redox homeostasis. Advances in mitochondrial research during the last two decades provide solid evidence that these organelles are deeply integrated with the rest of the cell and multiple mechanisms are in pla...

A passage to India's HIV epidemics: sending out an SOS.

The official view is that India's epidemics are driven, directly and indirectly, by heterosexual prostitution. Review of available evidence by researchers in India undermines this weakly supported orthodoxy and suggests that correcting weaknesses in its AIDS surveillance system can lead to a more reliable picture of HIV propagation and hence to evidence-based interventions. Contenders for leadi...

Sorting out typicality with the inverse moment matrix SOS polynomial

We study a surprising phenomenon related to the representation of a cloud of data points using polynomials. We start with the previously unnoticed empirical observation that, given a collection (a cloud) of data points, the sublevel sets of a certain distinguished polynomial capture the shape of the cloud very accurately. This distinguished polynomial is a sum-of-squares (SOS) derived in a simp...

Determining an appropriate sending rate over an underutilized network path

Determining an appropriate sending rate when beginning data transmission into a network with unknown characteristics is a fundamental issue in best-effort networks. Traditionally, the slow-start algorithm has been used to probe the network path for an appropriate sending rate. This paper provides an initial exploration of the efficacy of an alternate scheme called Quick-Start, which is designed...